Genetics Canada

Pulmonary Hypoplasia with Anasarca

Pulmonary Hypoplasia with Anasarca (PHA) is a lethal disorder linked to a genetic condition caused by a recessive mutation. PHA-affected calves are born dead with underdeveloped lungs (Pulmonary Hypoplasia) and swelling caused by excessive fluid retention (Anasarca).

Zoetis Genetics is now offering a diagnostic test for the genetic condition PHA. The gene mutation responsible for PHA has been identified and a diagnostic test has been developed by Dr. Jon Beever at the University of Illinois. Zoetis Genetics has licensed the test and Dr. Beever has validated its results.

Expand All
  • Testing of suspect animals is essential to avoid the negative impact of PHA and propagation of the recessive gene.

    Samples for testing may be submitted in one of the following forms:

    • Hair follicles. When sending hair samples, please make sure at least 25 follicles (bulb intact) are included to ensure an adequate volume of DNA to complete the test.
    • Blood collector cards
    • Semen samples